HORDB

ID: hor001595
Uniprot ID: Q07981
Protein name: FMRFamide-like
Gene name: NA
Organism: Cornu aspersum (Brown garden snail) (Helix aspersa)
Family: FARP (FMRFamide related peptide) family
Source: animal
Expression: Central nervous system.
Disease: NA
Comments: NA
Taxonomy: Cornu (subgenus), Cornu (genus), Helicidae (family), Helicoidea (superfamily), Helicina, Stylommatophora (order), Eupulmonata (superorder), Panpulmonata, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: SYGWAEGDTTDNEYLRF
Length: 17(20-36)
Propeptide: MTSLCLTIAPAVLSLICLSSYGWAEGDTTDNEYLRFGRENNNGYIRFGRNDPFLRFGKKSDPFLRFGKQDPFLRIGRQDPFLRFGKQDPFLRFGKQDPFLRIGKQDPFLRFGRSEPYLRFGRNDPYLRFGRNDPYLRFGRNDPYLRFGRNDPYLRFGKNDPFLRFGKSVDGEIEAGVDAVTLSREHEFAHENAASDRQKRSAYTDAIDKDNSLTSLVREAREASDSNGQINDGKVVEVPVFRDTRNGHYMRFGKK
Signal peptide: MTSLCLTIAPAVLSLICLS
Modification: T17 Phenylalanine amide
Glycosylation: NA
Mutagenesis: NA

Function: Can function as both cardioregulatory hormones and transmitters and may regulate cardiovascular function.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001595_AF2.pdb

hor001595_ESM.pdb

Mass:	230965	Formula:	C90H122N22O32
Absent amino acids:	CHIKMPQV	Common amino acids:	DEGTY
pI:	3.74	Basic residues:	1
Polar residues:	8	Hydrophobic residues:	4
Hydrophobicity:	-118.24	Boman Index:	-4752
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	28.82
Instability Index:	532.35	Extinction Coefficient cystines:	8480
Absorbance 280nm:	530